References for the risk reduction booklet
| 1. | Braak, H. and Braak, E. (1994). Diagnosis of Alzheimer’s disease: development of cytoskeletal changes and staging of Alzheimer related intraneuronal pathology. Neurobiology of Aging 15 S141. |
| 2. | Shumaker, S et al (2003). Oestrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. The Women’s Health Initiative Memory Study: a randomized controlled trial. Journal of the American Medical Association 289 2651-62. |
| 3. | www.patient.co.uk |
| 4. | Hebert, L E et al (1995). Age-specific incidence of Alzheimer’s disease in a community population. Journal of the American Medical Association 273 1354-9. |
| 5. | Gilleard, C J (2000). Is Alzheimer's disease preventable? A review of two decades of epidemiological research. Aging & Mental Health 4(2) May 101-18. |
| 6. | Launer, L J et al (1999). Rates and risk factors for dementia and Alzheimer’s disease. Results from EURODEM pooled analyses. Neurology 52 78-84. |
| 7. | Hebert, L E et al (2001). Is the risk of developing Alzheimer's disease greater for women than for men? American Journal of Epidemiology 153(2) 132-136. |
| 8. | Ruitenberg, A et al (2001). Incidence of dementia: does gender make a difference? Neurobiology of Aging 22(4) July-Aug 575-80. |
| 9. | www.alzscot.org/pages/info/dementiafacts.htm |
| 10. | Kivipelto, M et al (2005). Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Archives of Neurology 62(10) Oct 1556-1560. |
| 11. | Whitmer, R A et al (2005). Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. British Medical Journal doi:10.1136/bmj.38446.466238.E0 (published 16 May 2005). |
| 12. | www.bpassoc.org.uk |
| 13. | Kivipelto, M et al (2001). Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study. British Medical Journal 322 16 June 1447-1451. |
| 14. | Forette, F et al (2002). The prevention of dementia with antihypertensive treatment. New evidence from the Systolic Hypertension in Europe (Syst-Eur) study. Archives of Internal Medicine 162 2046-2052. |
| 15. | Bosch, J et al (2002). Use of ramipril in preventing stroke: double blind randomised trial. British Medical Journal 324 699-702. |
| 16. | Tzourio, C et al (2003). Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Archives of Internal Medicine 163 1069-75. |
| 17. | Reiss, A B (2005). Cholesterol and apolipoprotein E in Alzheimer's disease. American Journal of Alzheimer's Disease 20 (2) 91-96. |
| 18. | Medina, J (2003). Cholesterol and the risk for Alzheimer's disease. Geriatric Times 4(5) 17-18. |
| 19. | Rea, T D et al (2005). Statin use and the risk of incident dementia. The Cardiovascular Health Study. Archives of Neurology 62 July 1047-1051. |
| 20. | Breteler, M M (2000). Vascular risk factors for Alzheimer’s Disease: an epidemiologic perspective. Neurobiology of Aging 21(2) 153-60. |
| 21. | Wolozin, B et al (2000). Decreased prevalence of Alzheimer Disease associated with 3-Hydroxy-3-Methylglutaryl Coenzynme a Reductase Inhibitors. Archives of Neurology 57(10) 1439-43. |
| 22. | Morris, M C et al (2003). Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Archives of Neurology 60 940-946. |
| 23. | Morris, M C et al (2005). Fish consumption and cognitive decline with age in a large community study. Archives of Neurology 62 1849-1853. |
| 24. | Barberger-Gateau, P et al (2002). Fish, meat, and risk of dementia: cohort study. British Medical Journal 325 932-3. |
| 25. | Hooper, L et al (2006). Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review. British Medical Journal 332 752-60. |
| 26. | Burr, M L et al (2003). Lack of benefit of dietary advice to men with angina: results of a controlled trial. European Journal of Clinical Nutrition 57 193-200. |
| 27. | Mental Health Foundation (2006). Feeding minds: the impact of foods on mental health. London: MHF. |
| 28. | Morris, M (2004). Diet and Alzheimer’s disease: what the evidence shows. Medscape General Medicine 6(1) Jan-March 48. (published online). |
| 29. | Morris, M et al (2003). Dietary fats and the risk of incident Alzheimer disease. Archives of Neurology 60(2) Feb 194-200. |
| 30. | Luchsinger, J A et al (2002). Caloric intake and the risk of Alzheimer disease. Archives of Neurology 59 1258-63. |
| 31. | Engelhart, M J et al (2002). Diet and risk of dementia: does fat matter? Neurology 59 1915-21. |
| 32. | Petot, G J et al (2002). Dietary fat intake in mid-adulthood and apolipoprotein E genotype as risk factors for Alzheimer’s disease. Conference proceedings 2002. 8th International Conference on Alzheimer’s Disease and Related Disorders. |
| 33. | Panza, F et al (2004). Mediterranean diet and cognitive decline. Public Health and Nutrition 7(7) Oct 959-63. |
| 34. | Scarmeas, N et al (2006). Mediterranean diet and risk for Alzheimer’s disease. Annals of Neurology Published online 18 April 2006. http://dx.doi.org/10.1002/ana.20854. |
| 35. | Engelhart, M et al (2002). Dietary intake of antioxidants and risk of Alzheimer’s disease. Journal of the American Medical Association 287(24) 26 June 3223-3229. |
| 36. | Luchsinger, J et al (2003). Antioxidant vitamin intake and risk of Alzheimer’s disease. Archives of Neurology 60(2) Feb 203-8. |
| 37. | Morris, M et al (2002). Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. Journal of the American Medical Association 287(24) 26 June 3230-7. |
| 38. | Malouf. R et al (2003). Folic acid with or without vitamin B12 for cognition and dementia. Cochrane Review. |
| 39. | Reynolds, E (2002). Folic acid, ageing, depression and dementia. British Medical Journal 324 22 June 1512-1515. |
| 40. | Corrada, M M et al (2005). Reduced risk of Alzheimer’s disease with high folate intake: the Baltimore Longitudinal Study of Aging. Alzheimer's & Dementia: the Journal of the Alzheimer's Association 1(1) July 11-18. |
| 41. | Wang, H-W et al (2001). Vitamin B12 and folate in relation to the development of Alzheimer’s disease. Neurology 56 1188-1194. |
| 42. | Seshadri, S et al (2002). Plasma homocysteine as a risk factor for dementia and Alzheimer’s disease. New England Journal of Medicine 356 476-83. |
| 43. | Clarke, R et al (1998). Folate, vitamin B12 and serum total homocysteine levels in confirmed Alzheimer disease. Archives of Neurology 55(11) Nov 1449-55. |
| 44. | Malouf, R et al (2003). Folic acid with or without vitamin B12 for cognition and dementia. Cochrane Review. |
| 45. | Kivipelto, M et al (2001). Midlife vascular risk factors and Alzheimer’s disease in later life: longitudinal population based study. British Medical Journal 322 16 June 1447-1451. |
| 46. | Ruitenberg, A et al (2001). Blood pressure and risk of dementia: results from the Rotterdam study and the Gothenburg H-70 Study. Dementia and Geriatric Cognitive Disorders 12(1) Jan-Feb 33-9. |
| 47. | Food Standards Agency Scotland in association with Health Living (2002). Salt. NHS Health Scotland, 2002. |
| 48. | Chest Heart and Stroke Scotland (2004). Cholesterol factsheet. Edinburgh: CHSS. |
| 49. | Moroney, J T et al (1999). Low-density lipoprotein cholesterol and the risk of dementia with stroke. Journal of the American Medical Association 281(3) 21 July 254-260. |
| 50. | Reiss, A B (2005). Cholesterol and apolipoprotein E in Alzheimer's disease. American Journal of Alzheimer's Disease 20 (2) 91-96. |
| 51. | Medina, J (2003). Cholesterol and the risk for Alzheimer's disease. Geriatric Times 4 (5) 17-18. |
| 52. | Whitmer, R A et al (2005). Obesity in middle age and future risk of dementia: a 27-year longitudinal population-based study. British Medical Journal 330 11 June 1360-4. |
| 53. | Gustafson, D et al (2003). An 18-year follow-up of overweight and risk of Alzheimer disease. Archives of Internal Medicine 163 14 July 1524-8. |
| 54. | Abbott, R D et al (2004). Walking and dementia in physically capable elderly men. Journal of the American Medical Association 292(12) 22/29 Sept 1447-53. |
| 55. | Larson, E B et al (2006). Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Annals of internal medicine 144 73-81. |
| 56. | Podewils, L J et al (2005). Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study. American Journal of Epidemiology 161 April 1-13. |
| 57. | Abbott, R D et al (2004). Walking and dementia in physically capable elderly men. Journal of the American Medical Association 292(12) 22/29 Sept 1447-53. |
| 58. | Podewils, L J et al (2005). Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study. American Journal of Epidemiology 161 April 1-13. |
| 59. | Weuve, J et al (2004). Physical activity, including walking, and cognitive function in older women. Journal of the American Medical Association 292(12) 22/29 Sept 1454-1461. |
| 60. | Larsen, E B et al (2006). Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Annals of Internal Medicine 144 73-81. |
| 61. | Rovio, S et al (2005). Leisure-time physical activity at midlife and the risk of dementia and Alzheimer’s disease. The Lancet Neurology 4(11) Nov 705-11. |
| 62. | Verghese, J et al (2003). Leisure activities and the risk of dementia in the elderly. New England Journal of Medicine 348 (25) 19 June 2508-16. |
| 63. | Ball, K et al (2002). Effects of cognitive training interventions with older adults: a randomized controlled trial. Journal of the American Medical Association 288(18) 2271-81. |
| 64. | Casel, C K (2002). Use it or lose it activity may be the best treatment for aging. Journal of the American Medical Association 288(18) 2333-34. |
| 65. | Scarmeas, N and Stern, Y (2004). Cognitive reserve: implications for diagnosis and prevention of Alzheimer’s disease. Current Neurology and Neuroscience Reports 4(5) 374-80. |
| 66. | Schofield, P (1999). Alzheimer’s disease and brain reserve. Australasian journal on ageing 18 10-14. |
| 67. | Valenzuela, M J and Sachdev, P (2006). Brain reserve and dementia: a systematic review. Psychological medicine 36(4) April 441-54. |
| 68. | www.novartisfound.org.uk/cog_reserve.htm Comment by Ian Deary. |
| 69. | Bennett, DA et al (2003). Education modifies the relation of AD pathology to level of cognitive function in older persons. Neurology 60(12) 1909-1915. |
| 70. | Scarmeas, N et al (2006). Education and rates of cognitive decline in incident Alzheimer’s disease. Journal of Neurology, Neurosurgery, and Psychiatry 77 308-16. |
| 71. | Friedland, R P et al (2001). Patients with Alzheimer’s disease have reduced activities in midlife compared with healthy control-group members. Proceedings of the National Academy of Sciences of the United States 98(6) 13 March 3440-5. |
| 72. | Verghese, J et al (2003). Leisure activities and the risk of dementia in the elderly. New England Journal of Medicine 348(25) 19 June 2508-2516. |
| 73. | BBC News online 20 June, 2003 |
| 74. | Wilson, R et al (2002). Participation in cognitively stimulating activities and risk of incident Alzheimer disease. Journal of the American Medical Association 287 742-8. |
| 75. | Bassuk, S S et al (1999). Social disengagement and incident cognitive decline in community-dwelling elderly persons. Annals of internal medicine 131(3) 3 Aug 165-73. |
| 76. | Barnes, L L et al (2004). Social resources and cognitive decline in a population of older African Americans and whites. Neurology 63(12) 2322-2326. |
| 77. | Bassuk, S S et al (1999). Social disengagement and incident cognitive decline in community-dwelling elderly persons. Annals of internal medicine 131(3) 3 Aug 165-73. |
| 78. | Fratiglioni, L et al (2000). Influence of social network on occurrence of dementia: a community-based longitudinal study. Lancet 355 15 April 1315-9. |
| 79. | Wang, H-X et al (2002). Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen Project. American Journal of Epidemiology 155(12) 1 June 1081-7. |
| 80. | Fratiglioni, L et al (2004). An active and socially integrated lifestyle in late life might protect against dementia. The Lancet Neurology 3(6) June 343-53. |
| 81. | Karp, A (2005). Psychosocial factors in relation to development of dementia in late-life: a life-course approach within the Kungsholmen Project. Stockholm: Karolinska Institutet. [Thesis]. |
| 82. | Singh-Manoux, A et al (2003). Leisure activities and cognitive function in middle age: evidence from the Whitehall II study. Journal of Epidemiology and Community Health 57 907-13. |
| 83. | Jorm, A F (2001). History of depression as a risk factor for dementia: an updated review. Australian and New Zealand Journal of Psychiatry 35(6) Dec 776-81. |
| 84. | Green, R C et al (2003). Depression as a risk factor for Alzheimer’s disease: the MIRAGE study. Archives of Neurology 60(5) 753-9. |
| 85. | Geda, Y et al (2005). Pessimism and depression increase dementia risk. Presentation to the American Academy of Neurology, Miami 14 April. |
| 86. | Birks, J and Grimley Evans, J (2002). Ginkgo Biloba for cognitive impairment and dementia. Cochrane Review. |
| 87. | Plassman, B et al (2000). Documented head injury in early adulthood and risk of Alzheimer’ s disease and other dementias Neurology 55 1158-1166. |
| 88. | Cooper, B (2002). Thinking preventively about dementia: a review. International Journal of Geriatric Psychiatry 17 895-906. |
| 89. | Cooper, B (2002) Thinking preventively about dementia: a review. International Journal of Geriatric Psychiatry 17 895-906. |
| 90. | Mulnard, R et al (2000). Estrogen replacement therapy for treatment of mild to moderate Alzheimer’s disease. Journal of the American Medical Association 283 1007-1015. |
| 91. | Seshadri, S et al (2001). Postmenopausal estrogen replacement therapy and the risk of Alzheimer’s disease. Archives of Neurology 58 435-440. |
| 92. | Hogervorst, E et al (2002). HRT to maintain cognitive function in women with dementia. Cochrane Review Library. |
| 93. | Shumaker, S et al (2003). Oestrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. The Women’s Health Initiative Memory Study: a randomized controlled trial. Journal of the American Medical Association 289 2651-62. |
| 94. | BBC News (2005) HRT the reality behind the hype news.bbc.co.uk/1/hi/health/4744919.stm |
| 95. | Scottish Intercollegiate Guidelines Network (2006) Management of people with dementia. NHS Quality Improvement Scotland. |
| 96. | Cooper, B (2002). Thinking preventively about dementia: a review. International Journal of Geriatric Psychiatry 17 895-906. |
| 97. | Bas, A et al (2001). Nonsteroidal anti-inflammatory drugs and the risk of Alzheimer’s disease. New England Journal of Medicine 345(21) 22 Nov 1515-21. |
| 98. | Tabet, N and Feldman, H (2003). Ibuprofen for Alzheimer’s disease. The Cochrane Database of Systematic Reviews. |
| 99. | Green, R et al (2002). Study adds to evidence that statins reduce risk of Alzheimer’s disease. British Medical Journal 324 7343. |
| 100. | Scott, H D and Laake, K (2001). Statins for the prevention of Alzheimer’s disease. The Cochrane Database of Systematic Reviews. |
| 101. | Rea, T et al (2005). Statin use and the risk of incident dementia. Archives of Neurology 62 7. |
| 102. | Zandi, P et al (2005). Do statins reduce risk of incident dementia and Alzheimer disease. Archives of Neurology 62 2. |
| 103. | Ruitenberg, A et al (2002). Alcohol consumption and risk of dementia: the Rotterdam Study The Lancet 359:281-286 |
| 104. | Anttila, T et al (2004). Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study. British Medical Journal 329 539. |
| 105. | Okello, E et al (2004). In vitro anti-B-secretese and dual anti-cholinesterase activities of Camellia sinensis L (tea) relevant to treatment of dementia. Phytotherapy Research 18 624-627. |
| 106. | Rezai-Zadeh, K et al (2005). Green tea epigallocatechin-3-Gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. Journal of Neuroscience 25(38) 8807-8814. |
| 107. | Kuriyama, S et al (2006). Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project. American Journal of Clinical Nutrition 83 (2) 355-361. |
| 108. | Lim, G P et al (2001). The curry spice curcumin reduces oxidative damage and amyloid pathology in a Alzheimer transgenic mouse. Journal of Neuroscience 21 8370-8377. |
| 109. | Yang F, et al (2005). Curcumin inhibits formation of amyloid oligomers and fibrils binds plaques and reduces amyloid. Journal of Biological Chemistry 280 (7) 5892-5901. |
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